Head to head · Protein Powder
Dymatize ISO100 Hydrolyzed Whey Protein Isolate vs RYSE Loaded Protein
Dymatize scores higher overall (8.7 vs 7.7 out of 10) and leads on all five factors we score.
Updated October 2026 from our full reviews · How we score
An all-isolate whey with a hydrolyzed fraction: 25 g protein and about 2.7 g leucine per 120-calorie scoop, with Informed Choice testing.
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Licensed dessert flavors and 25 g of whey per 33.9 g scoop made it a TikTok Shop best seller, but it isn't third-party certified and costs $1.85 a scoop.
We may earn a commission when you buy through these links — it never affects our scores. How we make money
We may earn a commission when you buy through these links — it never affects our scores. How we make money
The short answer
Choose Dymatize if…
- Lifters who want a low-carb, low-fat isolate
- People with mild lactose sensitivity
- Drug-tested athletes
- Calorie-conscious dieters
- You care most about efficacy, quality & purity, value, experience, transparency
Choose RYSE if…
- Flavor-first shoppers who want dessert- and cereal-style shakes
- People who struggle to finish plain chocolate or vanilla protein
- Adding protein to oatmeal, overnight oats or protein desserts
Side by side
| ISO100 Hydrolyzed Whey Protein Isolate | Loaded Protein | |
|---|---|---|
| Our score | 8.7 / 10 | 7.7 / 10 |
| Efficacy (30%) | 9.0 | 8.4 |
| Quality & Purity (25%) | 9.0 | 7.2 |
| Value (20%) | 8.0 | 7.2 |
| Experience (15%) | 8.9 | 8.6 |
| Transparency (10%) | 8.5 | 6.8 |
| Form | Powder | Powder |
| Serving | 1 scoop (32 g)71 servings per container | Approximately 1 Scoop (33.9g)27 servings per container |
| Price per serving | See retailer | $1.85 |
| Testing & certifications | Informed Choice | None verified |
| Dietary | Gluten-free | — |
| Key ingredients |
|
|
| Flavors | 8 (Gourmet Chocolate, Gourmet Vanilla, Fruity Pebbles…) | 8 (Jet-Puffed Marshmallow, Cinnamon Toast, Chocolate Cookie Blast…) |
| Creator video reviews | 5 | 6 |
Pros and cons
ISO100 Hydrolyzed Whey Protein Isolate
- 25 g of protein and about 2.7 g of leucine per 120-calorie scoop, all from whey isolate
- Informed Choice banned-substance mark on the label
- Only 2 g of carbohydrate and 1 g of sugar in Gourmet Chocolate
- Dymatize publishes a full amino acid profile for the flavor
- buyers frequently praise fast, clump-free mixing
- About $1.55 per serving for the 5 lb tub, pricier than whey blends
- Contains soy lecithin and is sweetened with sucralose (plus stevia in the current formula)
- Some buyers still report bloating despite the isolate base
- Evidence for a real-world benefit from hydrolysis is thin, so part of the premium is marketing
Loaded Protein
- 25 g of protein in a 130-calorie, 33.9 g scoop with 1 g of sugar, and whey isolate listed first
- Licensed flavors (Jet-Puffed, Little Debbie, Pop-Tarts, JIF) that creators consistently rate as accurate and dessert-like
- Creamy, thick texture that mixes easily in water or milk and works in oatmeal
- An accredited-lab test commissioned by Garage Gym Reviews put the Jet-Puffed Marshmallow flavor in its top 10% for label accuracy and heavy metals
- No added free amino acids such as glycine or taurine on the ingredient list
- No NSF Certified for Sport, Informed Sport or similar certification
- Isolate-to-concentrate ratio and amino acid profile are not disclosed, and the MCT and prebiotic extras are token amounts
- Very sweet, with sucralose, acesulfame potassium and artificial flavor; some buyers notice an aftertaste
- About $1.85 per serving at full price, plus frequent stock-outs and shipping complaints
Our verdicts
ISO100 Hydrolyzed Whey Protein Isolate
ISO100 is one of the most complete whey isolates you can buy: 25 g of protein per scoop with a published amino acid profile, minimal carbs and fat, and banned-substance certification. You pay a premium over whey blends, and the hydrolyzed angle is more marketing than proven performance edge, but for a lean, well-tested isolate that mixes easily it is a safe pick.
Full review
Loaded Protein
RYSE Loaded Protein delivers what its fans want: 25 g of whey in flavors that genuinely taste like the desserts on the label, with a creamy texture and just 1 g of sugar. The rest of the pitch is thinner, because the prebiotic and MCT additions are token amounts, the whey ratio is undisclosed and there is no third-party certification. It is a good pick for flavor-driven shoppers, while drug-tested athletes and value seekers have better options.
Full review
What creators say
Questions people ask
Is Dymatize better than RYSE?
Are Dymatize and RYSE third-party tested?
Who should choose Dymatize over RYSE?
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