Head to head · Weight Management
Lemme GLP-1 Daily (Reset GLP-1 Production Support Capsules) vs Thorne Berberine (Dual Action Phytosome & HCl)
Thorne scores higher overall (6.9 vs 5.9 out of 10), mainly on efficacy, quality & purity, value and experience. Lemme still leads on transparency.
Updated September 2026 from our full reviews · How we score
Three branded extracts (lemon, saffron, red orange) at their studied doses and cleanly tested. But the trials are small, it's no GLP-1 drug, and it costs $80 a month.
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NSF Contents Certified berberine in HCl and phytosome forms. Well made, but the average weight change in trials is about 2 lb and it interacts with many drugs.
We may earn a commission when you buy through these links — it never affects our scores. How we make money
We may earn a commission when you buy through these links — it never affects our scores. How we make money
The short answer
Choose Lemme if…
- Shoppers who prioritize clean-label testing
- People curious about saffron for snacking and cravings
- Anyone who values fully disclosed doses
- You care most about transparency
Choose Thorne if…
- People whose clinician recommends berberine
- Shoppers who want NSF-verified quality
- Supporting healthy blood sugar and cholesterol alongside diet
- You care most about efficacy, quality & purity, value, experience
- You want the lower cost per serving ($1.47)
Side by side
| GLP-1 Daily (Reset GLP-1 Production Support Capsules) | Berberine (Dual Action Phytosome & HCl) | |
|---|---|---|
| Our score | 5.9 / 10 | 6.9 / 10 |
| Efficacy (30%) | 5.0 | 5.5 |
| Quality & Purity (25%) | 8.0 | 9.0 |
| Value (20%) | 3.5 | 5.5 |
| Experience (15%) | 6.0 | 7.0 |
| Transparency (10%) | 8.5 | 8.0 |
| Form | Capsule | Capsule |
| Serving | 2 capsules30 servings per container | 2 capsules30 servings per container |
| Price per serving | $2.67 | $1.47 |
| Testing & certifications | Clean Label ProjectThird-party testedcGMP facility | NSF Contents Certified |
| Dietary | Vegetarian, Gluten-free | Gluten-free, Dairy-free, Soy-free |
| Key ingredients |
|
|
| Flavors | — | — |
| Creator video reviews | 3 | 3 |
Pros and cons
GLP-1 Daily (Reset GLP-1 Production Support Capsules)
- All three ingredients are disclosed and dosed to match their clinical studies
- Clean Label Project Certified with a Purity Award, and third-party tested
- Clearly states it is not a GLP-1 drug
- Vegetarian and gluten-free, with no synthetic colors
- No trial of the finished product, and the ingredient studies are small (30–60 people) and short
- $80 a month, about $2.67 a day
- 3.5-star Amazon average, with reports of stomachaches or constipation
- Named in a 2025 proposed class action over its GLP-1 marketing
Berberine (Dual Action Phytosome & HCl)
- NSF Contents Certified and made in Thorne's own U.S. facility
- Fully disclosed doses of two berberine forms
- Berberine has a meaningful research base for metabolic markers
- Gluten-, dairy- and soy-free
- Average weight loss in trials is under 1 kg
- Decreases CYP2D6, CYP2C9 and CYP3A4 activity, so it can interact with many drugs
- About $1.47–2.93 a day, depending on dose
- Digestive side effects are common when you start
Our verdicts
GLP-1 Daily (Reset GLP-1 Production Support Capsules)
Lemme did something unusual: it dosed every ingredient to match its research and labeled the product honestly as not a drug. But the evidence comes from small, short trials of individual ingredients, and nothing suggests effects remotely comparable to GLP-1 medications. At $80 a month it's hard to justify; if you want to experiment, single-ingredient saffron extracts cost far less.
Full review
Berberine (Dual Action Phytosome & HCl)
Thorne Berberine is a well-made, NSF-certified version of the most researched 'metabolic' botanical, and a sensible choice if your clinician suggests berberine. Keep expectations in check, though: the average weight change in trials is about 2 pounds. Its drug-interaction profile also means it isn't something to add casually if you take prescription medications.
Full review
What creators say
Questions people ask
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