Head to head · Vitamins & Minerals
Nature's Bounty Vitamin B-12 1,000 mcg vs PreserVision AREDS 2 Formula MiniGels
Nature's Bounty scores higher overall (8.5 vs 7.7 out of 10), mainly on efficacy, value and experience.
Updated October 2026 from our full reviews · How we score

A best-selling 1,000 mcg cyanocobalamin tablet at about 5 cents a day; small and easy to swallow, with no third-party seal.
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The exact NEI AREDS2 doses in small MiniGels: worthwhile for intermediate AMD, no help for healthy eyes, and 80 mg of zinc is double the adult upper limit.
We may earn a commission when you buy through these links — it never affects our scores. How we make money
We may earn a commission when you buy through these links — it never affects our scores. How we make money
The short answer
Choose Nature's Bounty if…
- Adults over 50 and others at higher risk of low B12
- People who eat few or no animal foods
- Budget shoppers
- You care most about efficacy, value, experience
Choose PreserVision if…
- Adults with intermediate AMD, or advanced AMD in one eye, whose eye doctor recommends AREDS2
- Current or former smokers who need a beta-carotene-free AREDS formula
- People who want the exact NEI-tested doses in small softgels
Side by side
| Vitamin B-12 1,000 mcg | AREDS 2 Formula MiniGels | |
|---|---|---|
| Our score | 8.5 / 10 | 7.7 / 10 |
| Efficacy (30%) | 8.8 | 8.4 |
| Quality & Purity (25%) | 7.2 | 7.4 |
| Value (20%) | 9.8 | 7.0 |
| Experience (15%) | 9.0 | 7.8 |
| Transparency (10%) | 7.5 | 7.3 |
| Form | Tablet | Softgel |
| Serving | 1 tablet200 servings per container | 1 Soft Gel (MiniGel)120 servings per container |
| Price per serving | See retailer | $0.26 |
| Testing & certifications | None verified | None verified |
| Dietary | Vegetarian, Gluten-free, Non-GMO, Soy-free, Dairy-free, Sugar-free | — |
| Key ingredients |
|
|
| Flavors | — | — |
| Creator video reviews | 1 | 6 |
Pros and cons
Vitamin B-12 1,000 mcg
- About $0.05 per day
- 1,000 mcg dose compensates for limited absorption of oral B12
- Small, coated tablets that are easy to swallow
- Non-GMO, gluten-free and suitable for vegetarians
- No USP or NSF certification
- Brand site shows an outdated %DV and the Amazon listing has copy errors
- Far more B12 than people with normal levels need
AREDS 2 Formula MiniGels
- Matches the NEI AREDS2 formula dose for dose: 500 mg C, 400 IU E, 80 mg zinc, 2 mg copper, 10 mg lutein, 2 mg zeaxanthin
- Backed by large NEI trials: about 25% lower risk of advanced AMD over five years in higher-risk patients
- Beta-carotene free, so it suits current and former smokers
- Small MiniGels that buyers find easy to swallow
- 80 mg of zinc is twice the 40 mg adult upper limit, and AREDS2 found 25 mg worked as well
- No proven benefit for healthy eyes, early AMD or cataracts
- About $0.52 a day at the brand's price, more than store-brand compare-to versions
- Contains gelatin, carmine and titanium dioxide; the only published OcuSorb absorption study was funded by its maker
Our verdicts
Vitamin B-12 1,000 mcg
For most people who need extra B12, this is the simplest and cheapest effective option: a well-studied form at a dose that compensates for limited absorption, in a tablet anyone can swallow. It lacks independent certification and its listings are sloppy, but the formula itself is sound.
Full review
AREDS 2 Formula MiniGels
For someone whose eye doctor has found intermediate AMD, or advanced AMD in one eye, it delivers the NEI-tested AREDS2 formula dose for dose, in a small, easy MiniGel. It does nothing proven for healthy eyes, early AMD or cataracts. Because the 80 mg of zinc is double the adult upper limit and AREDS2 saw no loss of benefit at 25 mg, ask your doctor whether a lower-zinc AREDS2 formula suits you.
Full review
What creators say
Questions people ask
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