
Nature's Bounty
Vitamin B-12 1,000 mcg
A best-selling 1,000 mcg cyanocobalamin tablet at about 5 cents a day; small and easy to swallow, with no third-party seal.

The exact NEI AREDS2 doses in small MiniGels: worthwhile for intermediate AMD, no help for healthy eyes, and 80 mg of zinc is double the adult upper limit.
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Last reviewed October 22, 2026 by the Nutrition Reviews Editorial Team · How we review
Our verdict
For someone whose eye doctor has found intermediate AMD, or advanced AMD in one eye, it delivers the NEI-tested AREDS2 formula dose for dose, in a small, easy MiniGel. It does nothing proven for healthy eyes, early AMD or cataracts. Because the 80 mg of zinc is double the adult upper limit and AREDS2 saw no loss of benefit at 25 mg, ask your doctor whether a lower-zinc AREDS2 formula suits you.
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PreserVision AREDS 2 Formula MiniGels deliver, in two softgels a day, exactly the nutrient doses the National Eye Institute (NEI) tested in AREDS2: 500 mg vitamin C, 180 mg vitamin E (400 IU), 80 mg zinc, 2 mg copper, 10 mg lutein and 2 mg zeaxanthin. Bausch + Lomb produced the trial formulations. In the original AREDS trial (2001), the formula lowered the risk of advanced AMD by about 25% over five years in people with intermediate AMD or advanced AMD in one eye. AREDS2 (2013) led to lutein and zeaxanthin replacing beta-carotene after more lung cancers appeared in the beta-carotene group (2.0% vs 0.9%), mostly in former smokers, and the 2022 ten-year follow-up found about 15% lower risk of late AMD with lutein/zeaxanthin than with beta-carotene.
The NEI found no benefit for people without AMD or with early AMD, says supplements cannot stop AMD from developing, and the formulas did not reduce cataracts. The 80 mg of zinc is twice the 40 mg adult upper limit; AREDS2 saw no difference at 25 mg, AREDS zinc groups had more genitourinary hospital admissions, and case reports describe copper deficiency with long-term use. The only published support we found for the newer OcuSorb lutein's "2x" absorption claim is a single-dose blood study funded by its ingredient maker, and the "#1 doctor recommended" badge cites only "data on file."
At the brand store, $30.99 buys a 60-day supply, about $0.52 a day. Walmart's Equate compare-to MiniGels cost about $0.37 a day but are not identical, listing 4 mg of copper daily. Buyers mostly take it on an eye doctor's advice and find the MiniGels easy to take; complaints center on price, occasional headaches or stomach upset, and hopes for sharper vision that the formula is not designed to deliver.
| Key ingredient | Per serving | Why it matters |
|---|---|---|
| Zinc (from zinc oxide) The AREDS trial dose, but twice the 40 mg adult upper limit; AREDS2 found no difference at 25 mg, long-term high zinc can deplete copper, and zinc interacts with some antibiotics. | 80 mg per day (40 mg per MiniGel) | The AREDS trial dose, but twice the 40 mg adult upper limit; AREDS2 found no difference at 25 mg, long-term high zinc can deplete copper, and zinc interacts with some antibiotics. |
| Vitamin C (ascorbic acid) Matches the AREDS and AREDS2 dose (556% DV across two MiniGels). | 500 mg per day | Matches the AREDS and AREDS2 dose (556% DV across two MiniGels). |
| Vitamin E (dl-alpha tocopheryl acetate) The trial dose of synthetic vitamin E; the NEI notes a 17% higher prostate cancer risk with 400 IU in the SELECT trial, and high doses can raise bleeding risk with blood thinners. | 180 mg (400 IU) per day | The trial dose of synthetic vitamin E; the NEI notes a 17% higher prostate cancer risk with 400 IU in the SELECT trial, and high doses can raise bleeding risk with blood thinners. |
| Lutein (marigold flower extract, OcuSorb) Replaced beta-carotene in AREDS2; OcuSorb raised blood levels in a single-dose study funded by its maker, while the outcome trials used earlier formulations. | 10 mg per day | Replaced beta-carotene in AREDS2; OcuSorb raised blood levels in a single-dose study funded by its maker, while the outcome trials used earlier formulations. |
| Zeaxanthin The AREDS2 dose; the label says it may come from marigold flower or paprika fruit extract. | 2 mg per day | The AREDS2 dose; the label says it may come from marigold flower or paprika fruit extract. |
| Copper (from cupric oxide) Included, as in the trials, to offset zinc-related copper deficiency. | 2 mg per day | Included, as in the trials, to offset zinc-related copper deficiency. |
Supplement Facts
Serving Size 1 Soft Gel (MiniGel)
* Percent Daily Values are based on a 2,000 calorie diet. † Daily Value not established.
Other ingredients: Ascorbic acid, dl-alpha tocopheryl acetate, gelatin, glycerin, zinc oxide, marigold flower extract, medium chain triglycerides, carmine, zeaxanthin§, cupric oxide, titanium dioxide. § May be sourced from marigold flower or paprika fruit extract.
Testing & quality
No independent certification (USP, NSF) is claimed. The brand says products are manufactured and packaged in the USA, and the NEI notes that Bausch & Lomb produced the formulations used in the AREDS and AREDS2 trials.
Goals it supports
Independent creators reviewing AREDS 2 Formula MiniGels on YouTube and TikTok.
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