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Head to head · Vitamins & Minerals

Nature's Bounty Vitamin B-12 1,000 mcg vs Thorne Iron Bisglycinate

Nature's Bounty and Thorne finish level in our scoring (8.5 vs 8.6), so the right pick depends on what you value most — Nature's Bounty is stronger on efficacy, value and experience, Thorne on quality & purity and transparency.

Updated September 2026 from our full reviews · How we score

A best-selling 1,000 mcg cyanocobalamin tablet at about 5 cents a day; small and easy to swallow, with no third-party seal.

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25 mg of chelated iron (Ferrochel bisglycinate) in a small, NSF Certified for Sport capsule; gentler than iron salts for most, but only for people who need iron.

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The short answer

Choose Nature's Bounty if…

  • Adults over 50 and others at higher risk of low B12
  • People who eat few or no animal foods
  • Budget shoppers
  • You care most about efficacy, value, experience

Choose Thorne if…

  • People with low ferritin who get stomach upset from ferrous sulfate
  • Menstruating women and athletes who need iron under medical guidance
  • Vegetarians with confirmed low iron
  • You care most about quality & purity, transparency

Side by side

Vitamin B-12 1,000 mcgIron Bisglycinate
Our score8.5 / 108.6 / 10
Efficacy (30%)8.88.5
Quality & Purity (25%)7.29.3
Value (20%)9.87.6
Experience (15%)9.08.6
Transparency (10%)7.59.0
FormTabletCapsule
Serving1 tablet200 servings per container1 capsule60 servings per container
Testing & certificationsNone verified
NSF Certified for Sport
DietaryVegetarian, Gluten-free, Non-GMO, Soy-free, Dairy-free, Sugar-freeGluten-free, Dairy-free, Soy-free
Key ingredients
  • Vitamin B12 (as cyanocobalamin)1,000 mcg
  • Iron (as Ferrochel ferrous bisglycinate chelate)25 mg
Flavors——
Creator video reviews15

Pros and cons

Vitamin B-12 1,000 mcg

  • About $0.05 per day
  • 1,000 mcg dose compensates for limited absorption of oral B12
  • Small, coated tablets that are easy to swallow
  • Non-GMO, gluten-free and suitable for vegetarians
  • No USP or NSF certification
  • Brand site shows an outdated %DV and the Amazon listing has copy errors
  • Far more B12 than people with normal levels need

Iron Bisglycinate

  • Iron amino-acid chelate, a form NIH says may cause fewer GI side effects
  • NSF Certified for Sport
  • 25 mg dose sits below the 45 mg upper limit
  • Small 18 mm capsule with a short ingredient list
  • About $0.27 per day, more than generic ferrous sulfate
  • Some users still report nausea on an empty stomach
  • No vitamin C or other cofactors included
  • Not appropriate without a confirmed need for iron

Our verdicts

Vitamin B-12 1,000 mcg

For most people who need extra B12, this is the simplest and cheapest effective option: a well-studied form at a dose that compensates for limited absorption, in a tablet anyone can swallow. It lacks independent certification and its listings are sloppy, but the formula itself is sound.

Full review

Iron Bisglycinate

If you have documented low iron and struggle with conventional iron pills, this is one of the best-tolerated and best-verified options available, at a fair premium. It is not something to take without a reason: check ferritin first, and space it from calcium, thyroid medication and zinc.

Full review

What creators say

Questions people ask

Is Nature's Bounty better than Thorne?
They score about the same in our reviews (8.5 vs 8.6 out of 10). Nature's Bounty leads on efficacy, value and experience; Thorne leads on quality & purity and transparency. Choose based on the factors that matter most to you.
Are Nature's Bounty and Thorne third-party tested?
Nature's Bounty has no independent certification we could verify; Thorne carries NSF Certified for Sport. Sport-level certifications screen for banned substances, which matters for drug-tested athletes.
Who should choose Nature's Bounty over Thorne?
Our reviews suggest Nature's Bounty is best for adults over 50 and others at higher risk of low B12, people who eat few or no animal foods and budget shoppers, while Thorne is best for people with low ferritin who get stomach upset from ferrous sulfate, menstruating women and athletes who need iron under medical guidance and vegetarians with confirmed low iron.

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