Skip to content
Nutrition Reviews

Head to head · Protein Powder

Optimum Nutrition Gold Standard 100% Whey vs RYSE Loaded Protein

Optimum Nutrition scores higher overall (8.7 vs 7.7 out of 10) and leads on all five factors we score.

Updated October 2026 from our full reviews · How we score

Higher score

The benchmark whey blend: 24 g of protein per 120-calorie scoop, Informed Choice certified, and a flavor lineup few rivals can match.

Check price on AmazonShop on TikTok Shop10.8K+ sold

We may earn a commission when you buy through these links — it never affects our scores. How we make money

Read the full review

Licensed dessert flavors and 25 g of whey per 33.9 g scoop made it a TikTok Shop best seller, but it isn't third-party certified and costs $1.85 a scoop.

Check price on AmazonShop on TikTok Shop493.0K sold

We may earn a commission when you buy through these links — it never affects our scores. How we make money

Read the full review

We may earn a commission when you buy through these links — it never affects our scores. How we make money

The short answer

Choose Optimum Nutrition if…

  • First-time protein powder buyers
  • Everyday post-workout shakes
  • Drug-tested athletes who want a certified product
  • People who like lots of flavor choice
  • You care most about efficacy, quality & purity, value, experience, transparency

Choose RYSE if…

  • Flavor-first shoppers who want dessert- and cereal-style shakes
  • People who struggle to finish plain chocolate or vanilla protein
  • Adding protein to oatmeal, overnight oats or protein desserts

Side by side

Gold Standard 100% WheyLoaded Protein
Our score8.7 / 107.7 / 10
Efficacy (30%)8.88.4
Quality & Purity (25%)9.07.2
Value (20%)8.37.2
Experience (15%)9.08.6
Transparency (10%)8.06.8
FormPowderPowder
Serving1 scoop (31 g)74 servings per containerApproximately 1 Scoop (33.9g)27 servings per container
Price per servingSee retailer$1.85
Testing & certifications
Informed Choice
None verified
DietaryGluten-free—
Key ingredients
  • Protein blend (whey protein isolate, whey protein concentrate, hydrolyzed whey protein)24 g protein
  • Naturally occurring BCAAs5.5 g
  • Acesulfame potassium
  • Whey protein (instantized whey protein isolate and concentrate)25 g protein
  • Medium-chain triglyceride (MCT) powder
  • Organic agave inulin
  • Sucralose and acesulfame potassium
Flavors8 (Double Rich Chocolate, Extreme Milk Chocolate, Vanilla Ice Cream…)8 (Jet-Puffed Marshmallow, Cinnamon Toast, Chocolate Cookie Blast…)
Creator video reviews56

Pros and cons

Gold Standard 100% Whey

  • 24 g of protein in a 120-calorie, 31 g scoop (about 77% protein by weight)
  • Informed Choice certified and regularly tested for banned substances
  • More than 20 flavors on the brand's US store, with consistently strong feedback on taste and mixability
  • Fully disclosed ingredient list with no proprietary blend
  • Widely available on Amazon, TikTok Shop and at major retailers
  • Sweetened with acesulfame potassium and uses artificial flavors
  • Contains whey concentrate, and a share of buyers report digestive discomfort
  • No longer cheap: about $1.39 per serving at typical retail prices for the 5 lb tub, and the brand-site list price is higher
  • Servings per tub vary by flavor (roughly 68 to 75 in 5 lb-class tubs), which complicates price comparisons

Loaded Protein

  • 25 g of protein in a 130-calorie, 33.9 g scoop with 1 g of sugar, and whey isolate listed first
  • Licensed flavors (Jet-Puffed, Little Debbie, Pop-Tarts, JIF) that creators consistently rate as accurate and dessert-like
  • Creamy, thick texture that mixes easily in water or milk and works in oatmeal
  • An accredited-lab test commissioned by Garage Gym Reviews put the Jet-Puffed Marshmallow flavor in its top 10% for label accuracy and heavy metals
  • No added free amino acids such as glycine or taurine on the ingredient list
  • No NSF Certified for Sport, Informed Sport or similar certification
  • Isolate-to-concentrate ratio and amino acid profile are not disclosed, and the MCT and prebiotic extras are token amounts
  • Very sweet, with sucralose, acesulfame potassium and artificial flavor; some buyers notice an aftertaste
  • About $1.85 per serving at full price, plus frequent stock-outs and shipping complaints

Our verdicts

Gold Standard 100% Whey

Gold Standard 100% Whey remains a default recommendation for good reason: a lean 24 g protein dose, banned-substance certification, and taste and mixability endorsed across about 100,000 buyer ratings. It is no longer a bargain, and the concentrate and artificial sweetener will not suit everyone, but few powders balance quality, variety and availability this well.

Full review

Loaded Protein

RYSE Loaded Protein delivers what its fans want: 25 g of whey in flavors that genuinely taste like the desserts on the label, with a creamy texture and just 1 g of sugar. The rest of the pitch is thinner, because the prebiotic and MCT additions are token amounts, the whey ratio is undisclosed and there is no third-party certification. It is a good pick for flavor-driven shoppers, while drug-tested athletes and value seekers have better options.

Full review

What creators say

Questions people ask

Is Optimum Nutrition better than RYSE?
In our scoring, Optimum Nutrition Gold Standard 100% Whey rates higher overall (8.7 vs 7.7 out of 10). Optimum Nutrition leads on efficacy, quality & purity, value, experience and transparency. Scores weigh efficacy, quality, value, experience and transparency.
Are Optimum Nutrition and RYSE third-party tested?
Optimum Nutrition carries Informed Choice; RYSE has no independent certification we could verify.
Who should choose Optimum Nutrition over RYSE?
Our reviews suggest Optimum Nutrition is best for first-time protein powder buyers, everyday post-workout shakes and drug-tested athletes who want a certified product, while RYSE is best for flavor-first shoppers who want dessert- and cereal-style shakes, people who struggle to finish plain chocolate or vanilla protein and adding protein to oatmeal, overnight oats or protein desserts.

More protein powder comparisons