Head to head · Protein Powder
Dymatize ISO100 Hydrolyzed Whey Protein Isolate vs Isopure Zero Carb Whey Protein Isolate
Dymatize scores higher overall (8.7 vs 7.8 out of 10) and leads on four of the five factors we score.
Updated September 2026 from our full reviews · How we score
An all-isolate whey with a hydrolyzed fraction: 25 g protein and about 2.7 g leucine per 120-calorie scoop, with Informed Choice testing.
We may earn a commission when you buy through these links — it never affects our scores. How we make money
A true zero-carb whey isolate: 25 g of protein plus a broad vitamin and mineral blend in a 110-calorie scoop, at a price above most rivals.
We may earn a commission when you buy through these links — it never affects our scores. How we make money
We may earn a commission when you buy through these links — it never affects our scores. How we make money
The short answer
Choose Dymatize if…
- Lifters who want a low-carb, low-fat isolate
- People with mild lactose sensitivity
- Drug-tested athletes
- Calorie-conscious dieters
- You care most about quality & purity, value, experience, transparency
Choose Isopure if…
- Keto and strict low-carb diets
- People who want added vitamins and minerals
- Those who prefer a less-sweet vanilla
Side by side
| ISO100 Hydrolyzed Whey Protein Isolate | Zero Carb Whey Protein Isolate | |
|---|---|---|
| Our score | 8.7 / 10 | 7.8 / 10 |
| Efficacy (30%) | 9.0 | 8.9 |
| Quality & Purity (25%) | 9.0 | 7.4 |
| Value (20%) | 8.0 | 6.8 |
| Experience (15%) | 8.9 | 7.8 |
| Transparency (10%) | 8.5 | 7.8 |
| Form | Powder | Powder |
| Serving | 1 scoop (32 g)71 servings per container | 1 scoop (31 g)40 servings per container |
| Testing & certifications | Informed Choice | cGMP facility |
| Dietary | Gluten-free | Gluten-free, Sugar-free, Keto-friendly |
| Key ingredients |
|
|
| Flavors | 8 (Gourmet Chocolate, Gourmet Vanilla, Fruity Pebbles…) | 6 (Creamy Vanilla, Cookies & Cream, Strawberries & Cream…) |
| Creator video reviews | 5 | 4 |
Pros and cons
ISO100 Hydrolyzed Whey Protein Isolate
- 25 g of protein and about 2.7 g of leucine per 120-calorie scoop, all from whey isolate
- Informed Choice banned-substance mark on the label
- Only 2 g of carbohydrate and 1 g of sugar in Gourmet Chocolate
- Dymatize publishes a full amino acid profile for the flavor
- buyers frequently praise fast, clump-free mixing
- About $1.55 per serving for the 5 lb tub, pricier than whey blends
- Contains soy lecithin and is sweetened with sucralose (plus stevia in the current formula)
- Some buyers still report bloating despite the isolate base
- Evidence for a real-world benefit from hydrolysis is thin, so part of the premium is marketing
Zero Carb Whey Protein Isolate
- 25 g of protein with 0 g carbs and 0 g sugar per 110-calorie scoop
- All of the protein comes from whey protein isolate
- Broad vitamin and mineral blend, including 100% of the Daily Value for vitamin B12
- Large review base on Amazon (4.6 stars from more than 13,000 ratings)
- No third-party banned-substance certification found; testing is done in-house
- About $2.24 per serving for the 40-serving tub, and more on the brand site
- Contains soy lecithin, sucralose, artificial flavor and xanthan gum
- Flavor and texture draw mixed feedback, with some reviewers calling it gritty or bland
Our verdicts
ISO100 Hydrolyzed Whey Protein Isolate
ISO100 is one of the most complete whey isolates you can buy: 25 g of protein per scoop with a published amino acid profile, minimal carbs and fat, and banned-substance certification. You pay a premium over whey blends, and the hydrolyzed angle is more marketing than proven performance edge, but for a lean, well-tested isolate that mixes easily it is a safe pick.
Full review
Zero Carb Whey Protein Isolate
Isopure Zero Carb does exactly what the name promises: 25 g of isolate protein with no carbs or sugar, plus a vitamin and mineral boost. It is a sensible pick for strict low-carb and keto eaters, but the lack of third-party certification, the artificial sweetener and a price well above rivals such as ISO100 keep it out of the top tier.
Full review
What creators say
Questions people ask
Is Dymatize better than Isopure?
Are Dymatize and Isopure third-party tested?
Who should choose Dymatize over Isopure?
More protein powder comparisons
Whey+ Grass-Fed Whey Protein Isolate vs 100% Grass-Fed Whey Protein Isolate
Clear Whey Isolate vs 100% Grass-Fed Whey Protein Isolate
Whey Protein vs 100% Grass-Fed Whey Protein Isolate
Whey+ Grass-Fed Whey Protein Isolate vs Clear Whey Isolate
Whey Protein vs Whey+ Grass-Fed Whey Protein Isolate
Whey Protein vs Clear Whey Isolate
See all protein powder, ranked