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Front of Isopure Zero Carb Creamy Vanilla 2.73 lb tub

Zero Carb Whey Protein Isolate

A true zero-carb whey isolate: 25 g of protein plus a broad vitamin and mineral blend in a 110-calorie scoop, at a price above most rivals.

7.8

Good

Nutrition Reviews score

Weighted across efficacy, quality, value, experience & transparency. See breakdown

Form
Powder
Serving
1 scoop (31 g)
Servings
40
Videos
4
cGMP facility
Gluten-freeSugar-freeKeto-friendly
Check price on AmazonShop on TikTok Shop450+ soldBuy from the brand

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Last reviewed September 29, 2026 by the Nutrition Reviews Editorial Team · How we review

Our verdict

Isopure Zero Carb does exactly what the name promises: 25 g of isolate protein with no carbs or sugar, plus a vitamin and mineral boost. It is a sensible pick for strict low-carb and keto eaters, but the lack of third-party certification, the artificial sweetener and a price well above rivals such as ISO100 keep it out of the top tier.

Best for

  • Keto and strict low-carb diets
  • People who want added vitamins and minerals
  • Those who prefer a less-sweet vanilla

Skip it if

  • Drug-tested athletes who need a certified product
  • People already taking a full multivitamin
  • Budget shoppers

How it scored

Our five-factor score out of 10. Factors are weighted by how much they matter to the outcome you’re paying for. Methodology

7.8
Good

out of 10

  • Efficacy30%8.9

    Key ingredients at clinically studied doses, and how strong the evidence is.

  • Quality & Purity25%7.4

    Third-party testing and certifications, manufacturing standards, contaminant testing, recall history.

  • Value20%6.8

    Cost per effective serving compared with category peers.

  • Experience15%7.8

    Taste, mixability, texture and tolerability from aggregated buyer and creator feedback.

  • Transparency10%7.8

    Full label disclosure (no proprietary blends), available COAs, honest marketing.

Our review

Isopure Zero Carb has long been a fixture for low-carb dieters (the brand dates the introduction of Isopure to 1998), and it still delivers exactly what that audience wants. A 31 g scoop of Creamy Vanilla provides 25 g of protein from whey protein isolate with 0 g of carbohydrate, 0 g of sugar and 0.5 g of fat, for 110 calories.

Unlike most whey powders, it also carries a vitamin and mineral premix. One scoop supplies around a third of the Daily Value for many nutrients, including 100% of vitamin B12, 90% of chromium and 60% of copper. That is convenient for some people, but anyone already taking a multivitamin or drinking several shakes a day should tally their total intake.

Protein quality is not in question: whey isolate is well studied for supporting muscle protein synthesis, and 25 g per serving sits in the effective range for most adults. The weaker points are verification and cost. We did not find a third-party banned-substance certification for this powder; the brand says its products are made under FDA Good Manufacturing Practices and tested by its own quality assurance labs. The ingredient list also includes soy lecithin, sucralose, artificial flavor and xanthan gum.

On Amazon the Creamy Vanilla tub holds 4.6 stars across more than 13,000 ratings. Buyers like that it is not overly sweet, mixes well and sits easily on the stomach, though some find the texture gritty. Creator reviews are cooler on flavor, often calling the vanilla thin or basic. At about $2.24 per serving for the current 40-serving tub, it is one of the pricier mainstream isolates.

What’s inside

Key ingredientPer serving
Whey protein isolate

The only protein source; filtered to remove nearly all carbohydrate, fat and sugar.

25 g protein
Vitamin and mineral blend

Adds 20+ micronutrients per scoop, e.g. 100% DV vitamin B12, 90% DV chromium and 60% DV copper.

—
Sucralose

Non-nutritive sweetener that keeps sugar at 0 g; amount not disclosed.

—

Nutrition Facts

Serving Size 31 g (About 1 Scoop)

Servings Per Container About 44

Amount Per Serving% Daily Value
Calories 110
Total Fat 0.5 g1%
Cholesterol 5 mg2%
Sodium 190 mg8%
Total Carbohydrate 0 g0%
Total Sugars 0 g
Includes 0 g Added Sugars 0 g0%
Protein 25 g50%
Calcium 370 mg30%
Potassium 100 mg2%
Vitamin A 300 mcg35%
Vitamin C 15 mg15%
Vitamin E 5 mg35%
Thiamin 0.37 mg30%
Riboflavin 0.43 mg35%
Niacin 5 mg30%
Vitamin B6 0.5 mg30%
Folate 165 mcg DFE (100 mcg folic acid)40%
Vitamin B12 2.43 mcg100%
Pantothenic Acid 2.5 mg50%
Phosphorus 280 mg20%
Iodine 37 mcg25%
Magnesium 115 mg25%
Zinc 4.1 mg35%
Selenium 17 mcg30%
Copper 0.56 mg60%
Manganese 0.5 mg20%
Chromium 30 mcg90%
Molybdenum 18 mcg40%
Chloride 70 mg4%

* Percent Daily Values are based on a 2,000 calorie diet. † Daily Value not established.

Other ingredients: Whey protein isolate, vitamin and mineral blend (calcium phosphate, magnesium oxide, ascorbic acid, niacinamide, d-alpha tocopheryl acetate, zinc oxide, silicon dioxide, calcium d-pantothenate, vitamin a acetate, potassium iodide, manganese sulfate, chromium chloride, copper sulfate, pyridoxine hydrochloride, riboflavin, sodium molybdate, sodium selenite, thiamine mononitrate, folic acid, cyanocobalamin), soy lecithin, natural and artificial flavor, salt, sucralose, xanthan gum.

Contains: Milk and soy.

Panel shown for the Creamy Vanilla (3 lb tub) version. Transcribed from the manufacturer’s label (vitacost.com). Formulas change — always check the label on the product you buy.

Flavors & variants

Creamy VanillaCookies & CreamStrawberries & CreamBanana CreamVanilla Salted CaramelUnflavored

Testing & quality

Brand states products are made under FDA Good Manufacturing Practices and tested by its own quality assurance labs; no third-party banned-substance certification found for the Zero Carb powder.

Creator video reviews

Independent creators reviewing Zero Carb Whey Protein Isolate on TikTok and YouTube.

1 positive2 mixed1 critical

Pros & cons

What we like

  • 25 g of protein with 0 g carbs and 0 g sugar per 110-calorie scoop
  • All of the protein comes from whey protein isolate
  • Broad vitamin and mineral blend, including 100% of the Daily Value for vitamin B12
  • Large review base on Amazon (4.6 stars from more than 13,000 ratings)

Watch-outs

  • No third-party banned-substance certification found; testing is done in-house
  • About $2.24 per serving for the 40-serving tub, and more on the brand site
  • Contains soy lecithin, sucralose, artificial flavor and xanthan gum
  • Flavor and texture draw mixed feedback, with some reviewers calling it gritty or bland

Questions buyers ask

What is the difference between Isopure Zero Carb and Low Carb?
Both provide 25 g of whey isolate protein per scoop and both list zero sugar. Zero Carb flavors such as Creamy Vanilla list 0 g of carbohydrate, while Low Carb flavors, which include Dutch Chocolate, contain a small amount. The brand now sells both under a single Isopure Flavored Protein listing, so check the label of the flavor you choose.
Do I need the added vitamins and minerals?
Most people eating a varied diet do not. Each scoop supplies roughly 15% to 100% of the Daily Value for more than 20 nutrients, so several shakes a day plus a multivitamin can push chromium, copper or vitamin A well past 100% of the Daily Value. That is rarely a problem for occasional use, but it is worth tallying if you stack fortified products.
Is Isopure Zero Carb keto-friendly?
With 0 g of carbohydrate and 0 g of sugar per Creamy Vanilla scoop, the Zero Carb flavors fit easily into ketogenic or very-low-carb eating plans. Keep in mind that it is sweetened with sucralose and contains soy lecithin, which some keto dieters prefer to avoid.
Sources we checked (5)
  1. 1.theisopurecompany.com/products/flavored-protein-powder
  2. 2.vitacost.com/products/isopure-zero-carb-protein-powder-creamy-vanilla-3-lb-1-36-kg
  3. 3.amazon.com/dp/B000E95HP0
  4. 4.shop.tiktok.com/us/pdp/whey-protein-isolate-by-isopure-zero-low-carb-25g-protein-1-lb
  5. 5.theisopurecompany.com/pages/we-are

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Read the research