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Head to head · Protein Powder

Dymatize ISO100 Hydrolyzed Whey Protein Isolate vs Orgain Organic Protein Plant-Based Protein Powder

Dymatize scores higher overall (8.7 vs 7.5 out of 10), mainly on efficacy, quality & purity, experience and transparency. Orgain still leads on value.

Updated September 2026 from our full reviews · How we score

Higher score

An all-isolate whey with a hydrolyzed fraction: 25 g protein and about 2.7 g leucine per 120-calorie scoop, with Informed Choice testing.

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A budget USDA Organic vegan blend with 21 g protein and 7 g fiber per serving; a 2026 heavy-metals lawsuit against Costco is a key caveat.

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The short answer

Choose Dymatize if…

  • Lifters who want a low-carb, low-fat isolate
  • People with mild lactose sensitivity
  • Drug-tested athletes
  • Calorie-conscious dieters
  • You care most about efficacy, quality & purity, experience, transparency

Choose Orgain if…

  • Dairy-free and vegan diets
  • Budget-conscious smoothie users
  • Shoppers who want USDA Organic ingredients
  • You care most about value

Side by side

ISO100 Hydrolyzed Whey Protein IsolateOrganic Protein Plant-Based Protein Powder
Our score8.7 / 107.5 / 10
Efficacy (30%)9.07.6
Quality & Purity (25%)9.06.5
Value (20%)8.08.4
Experience (15%)8.98.0
Transparency (10%)8.57.0
FormPowderPowder
Serving1 scoop (32 g)71 servings per container2 scoops (46 g)20 servings per container
Testing & certifications
Informed Choice
USDA OrganicKosher
DietaryGluten-freeVegan, Dairy-free, Soy-free, Gluten-free, Organic, Non-GMO
Key ingredients
  • Hydrolyzed whey protein isolate and whey protein isolate25 g protein
  • Leucine (naturally occurring)2,677 mg
  • BCAAs (naturally occurring)5.5 g
  • Sucralose and steviol glycosides (stevia)
  • Organic protein blend (pea, brown rice and mung bean protein, chia seed)21 g protein
  • Organic agave inulin and acacia fiber7 g total dietary fiber
  • Organic Reb A (stevia extract)
Flavors8 (Gourmet Chocolate, Gourmet Vanilla, Fruity Pebbles…)8 (Creamy Chocolate Fudge, Vanilla Bean, Peanut Butter…)
Creator video reviews54

Pros and cons

ISO100 Hydrolyzed Whey Protein Isolate

  • 25 g of protein and about 2.7 g of leucine per 120-calorie scoop, all from whey isolate
  • Informed Choice banned-substance mark on the label
  • Only 2 g of carbohydrate and 1 g of sugar in Gourmet Chocolate
  • Dymatize publishes a full amino acid profile for the flavor
  • buyers frequently praise fast, clump-free mixing
  • About $1.55 per serving for the 5 lb tub, pricier than whey blends
  • Contains soy lecithin and is sweetened with sucralose (plus stevia in the current formula)
  • Some buyers still report bloating despite the isolate base
  • Evidence for a real-world benefit from hydrolysis is thin, so part of the premium is marketing

Organic Protein Plant-Based Protein Powder

  • Low cost for an organic protein (about $1.60 per serving on Amazon)
  • USDA Organic, vegan and made without soy, dairy or gluten ingredients
  • 7 g of fiber and less than 1 g of sugar per serving
  • Huge review base: 4.5 stars from more than 65,000 buyer ratings
  • A July 2026 proposed class action alleges undisclosed lead, cadmium and arsenic; Orgain says its products are safe
  • Only 21 g of protein per 46 g serving, with the lower leucine typical of plant blends
  • No published batch heavy-metal testing or sport certification
  • Texture can be gritty or slightly chunky in water, according to some reviewers

Our verdicts

ISO100 Hydrolyzed Whey Protein Isolate

ISO100 is one of the most complete whey isolates you can buy: 25 g of protein per scoop with a published amino acid profile, minimal carbs and fat, and banned-substance certification. You pay a premium over whey blends, and the hydrolyzed angle is more marketing than proven performance edge, but for a lean, well-tested isolate that mixes easily it is a safe pick.

Full review

Organic Protein Plant-Based Protein Powder

Orgain Organic Protein is an affordable, widely available organic vegan powder that most buyers find pleasant in smoothies. Its protein per serving is modest, and the 2026 heavy-metals lawsuit plus the lack of published contaminant testing mean shoppers who prioritize purity may prefer a plant protein with third-party certification.

Full review

What creators say

Questions people ask

Is Dymatize better than Orgain?
In our scoring, Dymatize ISO100 Hydrolyzed Whey Protein Isolate rates higher overall (8.7 vs 7.5 out of 10). Dymatize leads on efficacy, quality & purity, experience and transparency; Orgain leads on value. Scores weigh efficacy, quality, value, experience and transparency.
Are Dymatize and Orgain third-party tested?
Dymatize carries Informed Choice; Orgain has no independent certification we could verify.
Who should choose Dymatize over Orgain?
Our reviews suggest Dymatize is best for lifters who want a low-carb, low-fat isolate, people with mild lactose sensitivity and drug-tested athletes, while Orgain is best for dairy-free and vegan diets, budget-conscious smoothie users and shoppers who want USDA Organic ingredients.

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