Betaine supplements, compared
5 products we’ve reviewed list betaine as a key ingredient. Here’s what it does, what the research uses — and how much each product actually contains.
What it is
Also called trimethylglycine; found in beets, spinach and whole grains. Small studies in men show conflicting results and modest improvements at best.
What the research uses
Studies typically used 2–5 g a day for up to 15 days.
Educational information, not medical advice. Talk to a healthcare professional before starting a supplement, especially if you are pregnant, nursing or take medication.
Every product, dose by dose
| Product | Betaine per serving | Form | Score |
|---|---|---|---|
 Informed Choice | 2,500 mgBetaPure betaine anhydrous | Powder | 8.5 |
 Third-party testedcGMP facility | 2,500 mgBetaine anhydrous | Powder | 8.3 |
 Third-party tested | 2,000 mg per scoopBetaine anhydrous | Powder | 8.2 |
 | 2,500 mgBetaine anhydrous | Powder | 8.2 |
 Informed Sport | 2.5 gBetaPower betaine anhydrous | Powder | 8.1 |
Amounts are per serving as printed on each label. “Not disclosed” usually means the ingredient sits inside a proprietary blend.
Questions people ask
How much betaine do studies use?
Studies typically used 2–5 g a day for up to 15 days.
Which betaine supplement scores highest?
In our reviews, Transparent Labs BULK Pre-Workout scores highest at 8.5/10, followed by Legion Pulse Pre-Workout (8.3) and Gorilla Mind Gorilla Mode Pre-Workout (8.2). Scores weigh efficacy, quality, value, experience and transparency — not just the dose.
How much betaine is in these products?
It varies by product and serving size — for example Transparent Labs BULK Pre-Workout (2,500 mg), Legion Pulse Pre-Workout (2,500 mg), Gorilla Mind Gorilla Mode Pre-Workout (2,000 mg per scoop). The table above lists the amount per serving for every product we've reviewed.