Best Value
Centrum
Adults Multivitamin
8.0Good
The drugstore benchmark: one tablet with 24 nutrients near 100% DV, including iron, iodine and folic acid, for about six cents a day. No third-party seal.
4 videosMultivitamins
Prenatal Multi + DHA Softgels
A USP Verified one-a-day prenatal softgel with 800 mcg folic acid, 27 mg iron, 150 mcg iodine and 200 mg DHA, but no choline and a divisive scent.
8.1
Good
Nutrition Reviews score
Weighted across efficacy, quality, value, experience & transparency. See breakdown
- Form
- Softgel
- Serving
- 1 softgel
- Servings
- 110
- Videos
- 6
USP Verified
Gluten-free
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Last reviewed October 22, 2026 by the Nutrition Reviews Editorial Team · How we review
Our verdict
Nature Made Prenatal Multi + DHA covers the essentials of a prenatal, folic acid, iron, iodine, vitamin D and 200 mg of DHA, with USP verification and one of the lowest daily costs in the category. Its shortcomings are the missing choline, minimal calcium and magnesium, and a scent that many pregnant buyers find hard to tolerate. It is a sound budget choice if you add choline-rich foods or a separate choline supplement and review your plan with your clinician.
Best for
- Women planning a pregnancy or pregnant who want a low-cost, USP Verified prenatal
- People who want iodine and DHA in a single daily softgel
- Anyone looking for folic acid at the dose the USPSTF recommends
Skip it if
- Vegetarians and vegans (gelatin and fish oil)
- People sensitive to scents during morning sickness
- Women told to take prescription-strength folic acid, for example after a prior neural tube defect pregnancy
How it scored
Our five-factor score out of 10. Factors are weighted by how much they matter to the outcome you’re paying for. Methodology
8.1
Goodout of 10
- Efficacy30%8.1
Key ingredients at clinically studied doses, and how strong the evidence is.
- Quality & Purity25%8.3
Third-party testing and certifications, manufacturing standards, contaminant testing, recall history.
- Value20%9.2
Cost per effective serving compared with category peers.
- Experience15%6.5
Taste, mixability, texture and tolerability from aggregated buyer and creator feedback.
- Transparency10%8.3
Full label disclosure (no proprietary blends), available COAs, honest marketing.
Our review
Nature Made Prenatal Multi + DHA, now labeled Prenatal Folic Acid + DHA, is one of the best-selling drugstore prenatals, and its core doses line up with U.S. guidance. One softgel supplies 800 mcg of folic acid (1,330 mcg DFE), the top of the 400 to 800 mcg range the U.S. Preventive Services Task Force recommends for anyone who could become pregnant. It adds 27 mg of iron (the pregnancy RDA), 150 mcg of iodine as potassium iodide (the daily supplement the American Thyroid Association advises), 1,000 IU of vitamin D3 and 200 mg of DHA from fish oil. All of the vitamin A comes from beta-carotene.
The gaps matter. There is no choline, although the pregnancy Adequate Intake is 450 mg and NIH reports that 90 to 95 percent of pregnant women fall short. Calcium (150 mg) and magnesium (45 mg) are token amounts, and selenium and copper are absent. On quality, the softgel carries the USP Verified mark, Nature Made says every prenatal lot is tested for heavy metals against California Proposition 65 levels, and FDA's recall database lists no recalls of this product. A 2025 class action alleged the softgels contain plastic chemicals such as phthalates; Pharmavite contested it.
At Walmart's price for the 100-count bottle it costs about 19 cents a day, versus about 40 cents on the brand site; the 110-count sold is the same formula. Tolerability is the weak spot. Buyers on Nature Made's own site report fishy-smelling batches, and since an orange scent was added many say it worsens morning sickness, while others prefer it. Some find the softgel large.
What’s inside
| Key ingredient | Per serving | Why it matters |
|---|---|---|
| Folate (as folic acid) Top of the USPSTF's 400 to 800 mcg range and the form used in the neural tube defect research; under the 1,000 mcg upper limit unless stacked with another folic acid product. Nature Made does not cite the study behind its 'clinically proven absorption' claim. | 1,330 mcg DFE (800 mcg folic acid) | Top of the USPSTF's 400 to 800 mcg range and the form used in the neural tube defect research; under the 1,000 mcg upper limit unless stacked with another folic acid product. Nature Made does not cite the study behind its 'clinically proven absorption' claim. |
| Iron (as ferrous fumarate) Equals the 27 mg pregnancy RDA; iron can cause nausea or constipation, and iron supplements must be kept away from children. | 27 mg | Equals the 27 mg pregnancy RDA; iron can cause nausea or constipation, and iron supplements must be kept away from children. |
| Iodine (as potassium iodide) Exactly the 150 mcg daily supplement the American Thyroid Association advises when planning a pregnancy, pregnant or breastfeeding (52% of the pregnancy DV). | 150 mcg | Exactly the 150 mcg daily supplement the American Thyroid Association advises when planning a pregnancy, pregnant or breastfeeding (52% of the pregnancy DV). |
| Omega-3 DHA (from fish oil concentrate, as ethyl esters) Meets the at-least-200 mg daily DHA target from an international expert consensus; comes with 60 mg EPA (260 mg omega-3s in total). | 200 mg | Meets the at-least-200 mg daily DHA target from an international expert consensus; comes with 60 mg EPA (260 mg omega-3s in total). |
| Vitamin D3 (as cholecalciferol) Above the 600 IU RDA for pregnancy and far below the 4,000 IU upper limit. | 25 mcg (1,000 IU) | Above the 600 IU RDA for pregnancy and far below the 4,000 IU upper limit. |
| Vitamin A (as beta-carotene) All from beta-carotene rather than preformed retinol, the form with an upper limit that matters in pregnancy (59% of the pregnancy DV). | 770 mcg | All from beta-carotene rather than preformed retinol, the form with an upper limit that matters in pregnancy (59% of the pregnancy DV). |
| Calcium (as calcium carbonate) Only 12% of the pregnancy DV; most of the 1,000 mg daily need has to come from food. | 150 mg | Only 12% of the pregnancy DV; most of the 1,000 mg daily need has to come from food. |
| Vitamin B12 (as cyanocobalamin) Twice the 2.6 mcg pregnancy RDA; NIH finds no evidence that B12 absorption differs by form. | 5.2 mcg | Twice the 2.6 mcg pregnancy RDA; NIH finds no evidence that B12 absorption differs by form. |
Supplement Facts
Serving Size 1 Softgel
Amount Per Serving% Daily Value
Calories 5
Cholesterol less than 5 mg1%
Vitamin A (as Beta Carotene) 770 mcg59%
Vitamin C (as Ascorbic Acid) 85 mg71%
Vitamin D3 (as Cholecalciferol) 25 mcg (1000 IU)167%
Vitamin E (as d-Alpha Tocopherol) 15 mg79%
Vitamin K (as Phytonadione) 90 mcg100%
Thiamin (as Thiamine Mononitrate) 1.4 mg100%
Riboflavin 1.4 mg88%
Niacin (as Niacinamide) 18 mg100%
Vitamin B6 (as Pyridoxine Hydrochloride) 1.9 mg95%
Folate 1330 mcg DFE (800 mcg Folic Acid)222%
Vitamin B12 (as Cyanocobalamin) 5.2 mcg186%
Biotin 30 mcg86%
Pantothenic Acid (as d-Calcium Pantothenate) 6 mg86%
Calcium (as Calcium Carbonate) 150 mg12%
Iron (as Ferrous Fumarate) 27 mg100%
Iodine (as Potassium Iodide) 150 mcg52%
Magnesium (as Magnesium Oxide) 45 mg11%
Zinc (as Zinc Oxide) 11 mg85%
Omega-3 Fatty Acids (from Fish Oil Concentrate)†† 260 mg*
Omega-3 Docosahexaenoic Acid (DHA)†† 200 mg*
Omega-3 Eicosapentaenoic Acid (EPA)†† 60 mg*
* Percent Daily Values are based on a 2,000 calorie diet. † Daily Value not established.
Other ingredients: Gelatin, Glycerin, Lecithin, Less than 2% of Soybean Oil, Dibasic Calcium Phosphate, Yellow Beeswax, Tocopherols, Resin, Ascorbyl Palmitate.
Flavors & variants
Orange scent
Testing & quality
Nature Made seeks USP Verification for many products, including its core multivitamins and single-nutrient tablets and softgels; USP's product finder lists Nature Made as a participating brand.
Goals it supports
Creator video reviews
Independent creators reviewing Prenatal Multi + DHA Softgels on YouTube and TikTok.
3 positive1 mixed2 critical
Pros & cons
What we like
- 800 mcg folic acid, 27 mg iron and 150 mcg iodine, matching USPSTF, RDA and American Thyroid Association targets
- 200 mg DHA plus 60 mg EPA from fish oil in the same softgel
- USP Verified, with lot-by-lot heavy-metal testing described by the brand
- About 19 to 40 cents a day, depending on bottle size and retailer
- Vitamin A comes entirely from beta-carotene, with no preformed retinol
Watch-outs
- No choline, despite a 450 mg Adequate Intake in pregnancy
- Only 150 mg calcium and 45 mg magnesium, and no selenium or copper
- The orange scent divides buyers, and some batches drew fishy-smell complaints
- Contains gelatin and fish oil, so it is not vegetarian
Questions buyers ask
Does Nature Made Prenatal Multi + DHA contain choline?
No. The softgel has no choline, although the Adequate Intake during pregnancy is 450 mg a day and NIH reports that 90 to 95 percent of pregnant women fall short. Eggs, meat, fish, dairy and soybeans are good sources. Nature Made also sells a bundle that adds a 265 mg choline capsule; ask your clinician whether you need a separate supplement.
Why do some bottles smell of oranges or fish?
Current bottles are orange-scented. Some buyers like it, but many reviewers say the citrus smell makes morning sickness worse, and before the change several batches drew complaints of a strong fishy smell and taste. Keeping the bottle tightly closed in a cool, dry place and taking the softgel with a meal, as the label directs, may help.
Has it been tested for heavy metals and plastic chemicals?
It is USP Verified, and Nature Made says every prenatal lot is tested for heavy metals against California Proposition 65 limits. A 2025 study of 47 prenatals found none above USP heavy-metal limits. A 2025 class action, citing independent tests that found low levels of phthalates in every prenatal they checked, alleged this softgel contains them; Pharmavite contested it, and court records show dismissal filings in April 2026.
Sources we checked (42)
- 1.naturemade.com/products/nature-made-prenatal-multi-dha-softgels
- 2.naturemade.com/products/nature-made-prenatal-multi-dha-softgels.js
- 3.cdn.shopify.com/s/files/1/0066/7569/3639/files/NM2749PK001706PRENATALMULTI_DHAback.jp
- 4.cdn.shopify.com/s/files/1/0066/7569/3639/files/NM2766PK001710PRENATALMULTI_DHAback.jp
- 5.api.ods.od.nih.gov/dsld/v9/label/241703
- 6.api.ods.od.nih.gov/dsld/s3/pdf/241703.pdf
- 7.api.ods.od.nih.gov/dsld/v9/label/280356
- 8.naturemade.com/pages/test-results
- 9.naturemade.com/products/prenatal-multi-softgels-choline-capsules
- 10.naturemade.com/pages/about-us
- 11.pharmavite.com/
- 12.amazon.com/dp/B07BXVFC32
- 13.walmart.com/ip/1971189050
- 14.uspreventiveservicestaskforce.org/uspstf/recommendation/folic-acid-for-the-prevention-of-neural-tube-de
- 15.ods.od.nih.gov/factsheets/Folate-HealthProfessional/
- 16.ods.od.nih.gov/factsheets/Choline-HealthProfessional/
- 17.ods.od.nih.gov/factsheets/Iodine-HealthProfessional/
- 18.ods.od.nih.gov/factsheets/Iron-HealthProfessional/
- 19.ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/
- 20.ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
- 21.ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
- 22.ods.od.nih.gov/factsheets/Calcium-HealthProfessional/
- 23.fda.gov/food/consumers/advice-about-eating-fish
- 24.pubmed.ncbi.nlm.nih.gov/17688705/
- 25.pubmed.ncbi.nlm.nih.gov/22579722/
- 26.pubmed.ncbi.nlm.nih.gov/40252729/
- 27.pmc.ncbi.nlm.nih.gov/articles/PMC12226752/
- 28.consumerreports.org/health/supplements/how-to-choose-a-prenatal-vitamin-a1197384921/
- 29.consumerreports.org/health/food-contaminants/prenatal-vitamins-testing-label-accuracy-a74
- 30.courtlistener.com/docket/69913847/lang-v-pharmavite-llc/
- 31.storage.courtlistener.com/recap/gov.uscourts.casd.811628/gov.uscourts.casd.811628.1.0.pdf
- 32.plasticlist.org/report
- 33.api.fda.gov/food/enforcement.json?search=recalling_firm:Pharmavite&limit=100
- 34.shop.tiktok.com/us/store/nature-made/7495307893427243665
- 35.prenatals.com/nature-made-prenatal-multi-dha-review/
- 36.youtube.com/watch?v=U_lX9pU7dn0
- 37.youtube.com/watch?v=Mdr0SK2Zdy8
- 38.youtube.com/watch?v=AxeGCubICLU
- 39.youtube.com/watch?v=tS-2uUyqztE
- 40.tiktok.com/@babybumpdietitian/video/7616103112691977502
- 41.tiktok.com/@randomthoughtswith.jess/video/7475815667829263662
- 42.quality-supplements.org/usp_verified_products?term%5B0%5D=brand%3ANature%20Made&term%5B1%5D=s
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